thyroid peroxidase inactivated by antioxidants

 

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Post:  I have been having blood tests done for the past 6 months or so. Firstly my GP told me I was pre-diabetic. My fasting glucose results over the past 6 months have been between 6.3-6.5 despite losing 10lbs in weight and doing hard exercise 5 days a week at the gym. Plus reducing sugars eaten. My thyroid antibodies are also high. But I don't quite understand my results. I have seen a rheumatoidoligist about my anti-nuclear factor. But he said my results were very low and nothing to worry about.
Can anyone explain them to me. My GP has referred me to an Endo. But I am awaiting an appointment.
I would like to know what questions to ask when I go for my appointment. I have normal BP. My cholesterol levels are good at 3.4. I am 50, female and possibly going through the menopause. I also need to lose another stone or two to come within normal weight ranges.


I suffer from carpal tunnel syndrome symptoms in both hands, which wake me up every night. But nerve conductive tests have told me I do not have CTS.

Blood Results of 1st test below: My 2nd thyroid AB tests were also high. I have to have a repeat test in November.

^06/03/2006 Autoantibody level Dr Susan
^6/03/2006 Thyroglobulin autoantibodies High_ /
"Thyroid AbS are associated with autoimmune
thyroid disease or other autoimmune diseases.
In euthyroid patients it indicates a risk
of developing Primary Myxoedema. i *** NUMERIC VALUE SUPPLIED: > 3000iu/mL *** Dr Susan
06/03/2006 Thyroid peroxidase antibody level High
*** NUMERIC VALUE SUPPLIED: = 933iu/mL *** Dr Susan 06/03/2006 Thyroid autoantibodies Dr Susan 06/03/2006 Parietal cell autoantibodies NEGATIVE
Dr Susan
06/03/2006 Anti smooth muscle autoantibod NEGATIVE
Dr Susan 06/03/2006 Anti-nuclear factor WEAK POSITIVE 1/40

 

Post: I have only seen my GP so far for blood tests. Last 2 tests have given high results, so I have been refered to an Endo. The tests that are due in November are clinical chemistry according to the blood sheet. Thyroid, lipids fasting & glucose fasting. The doc hasn't ticked the box for thyroid antibodies (immunology section).
I am only just starting to research Thyroid conditions. Hopefully things will be clearer when I have seen the Endo.
The results I have given are for March 2006. I had repeat tests done in August 2006 but I dont know what tests were done, other than they were thyroid and fasting glucose. Both AB and glucose results were still high.

 

Post: My TSH came back normal at 0.32 (was 12 - 3 months ago). I am on 100ug of thyroxine. They didn't check my antibodies which were over 1000 for TPO and over 500 for Antithy also 3 months ago. I've asked to get them checked again. Doc said that the antibody levels will never change - I will always have an auto-immune disease - my antibodies will always be attacking my thyroid. Is this true?

 

Reply:

Well I've done a bit of searching around and I have not found anything that says that antibodies will always attack the thyroid but let me just put a few things down and maybe we can come up with an answer.

Okay the term "autoimmune disease" in a book I have says this..."It refers to a group of more
serious illnesses that include diseases of the body including endocrine systems.
In all of these diseases the overall problem is that the bodies immune system misdirected and attacks organs in the body that it should be protecting".

I googled it and got this..."Autoimmune disease:- any disease in which the bodies immune system which is designed to protect the body from outside invaders like viruses and bacteria mistakes a normal part of the body for an invader and tries to destroy it".

I also googled this..."Antibodies:- proteins that the bodies immune system makes to invade bacteria and viruses".

Right so from that it's telling us that the immune system/antibodies attack and destroy the thyroid gland because they think it's an invader.

So would it figure that because we have a thyroid problem and our antibodies are attacking our thyroid then even with treatment they still will be attacking the gland but the tablets stop us from feeling the effects of this. Because if they stopped attacking we would have to stop taking thyroxine because the problem would have gone away.

Does that make any sense?

 

 

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